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Accelerator Mass Spectrometry was used to determine Delta14C values, and light isotope ratio mass spectrometry to determine d18O values. \r\nABSTRACT SUPPLIED BY ORIGINATOR: We present seasonal D14C and d18O measurements from a Galapagos coral sequence that grew during the early 20th century. Our results show that both D14C and d18O values are correlated with sea surface temperature in the Ni\u00f1o 3.4 region and are indicators of El Ni\u00f1o/Southern Oscillation. There is a significant inverse correlation between D14C and d18O values when D14C is lagged by ~2 months, indicating that sea surface temperature changes precede upwelling changes at this eastern equatorial location. We find that cold season low D14C values were higher after the Pacific Decadal Oscillation (PDO) changed from a positive to a negative phase. Cold season high d18O values were significantly higher after the PDO shift, as well. 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